The mad scientist Jesse Ezell has baked a little goodie into 2.5 you may find useful but you won't find it in the UI...
What he's done is make it so you can change the URL of the target service in a Pipeline. This means you can not only easily create an On Ramp pattern in Neuron you can create an Off Ramp as well!
The actual code you use looks like this:
context.Data.SetProperty("Addressing","To",[Insert your service url here]);
Pretty simple huh!
So when would you use this? One scenario that immediately leaps to mind is if the SOAP request is actually Neuron initiated instead of proxy intiated. In this case you don't have the benefits of an OnRamp available because the message is initiated from the API in a custom application or from an adapter.
Another scenario might involve a distributed environment where multiple locations have the exact same services logic but they have independent data stores.
An Off Ramp just like its On Ramp counterpart is binding specific.
It's awesome stuff. Give it a try!